Application: morphometry of nerve cross-sections

In this chapter, we illustrate the use of the EDT by propagation algorithm with a first medical imaging application, the automatic morphometry of nerve cross-sections. In this application, the EDT is used as a criterion to separate connected neuronal fibers and evaluate the myelin sheath thickness around the axons. First we describe the nature of the images to be treated and of the entities to detect. Then, we present the full segmentation procedure. Finally, we present typical results and study their validity.